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Clomicalm (Clomipramine) Tablets

$1.83

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Prescription Required

Elanco SKU: 10520-1

Strength: 5-mg
Size: 1 tablet
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Supports Dogs With Separation Anxiety and Behavioral Recovery 

Product Description 

Clomicalm is a veterinary prescription medication for dogs that helps manage separation anxiety when combined with behavior modification training. It works on central nervous system neurotransmitters to reduce anxiety-related behaviors such as destructive actions, excessive vocalization, and inappropriate elimination. The flavored tablets are designed for oral administration and are available in multiple strengths for accurate dosing based on body weight.

Please note that your order may be dispensed in a Hardy Paw Pharmacy vial. The manufacturer’s packaging image is provided for reference only.

Benefits

  • Targets Separation Anxiety: Helps reduce symptoms like barking, destructive behavior, drooling, and inappropriate elimination that come with canine separation anxiety.
  • Supports Behavior Training: Improves the effectiveness of desensitization and counterconditioning programs when used with professional behavior modification techniques.
  • Proven Clinical Improvement: Studies show quicker improvement in anxiety-related behaviors compared to therapy alone in affected dogs.  
  • Flexible Dosing Options: Can be given once daily or in smaller doses, based on how the canine responds and tolerates it, under veterinary supervision.  
  • Palatable Formulation: Tablets have meat components to make them more accepted and to ease oral administration in dogs.

Variants

Clomicalm (Clomipramine) Tablets is availabe in following strengths:

  • 5 mg Tablets
  • 20 mg Tablets
  • 80 mg Tablets

Ingredients 

Active Ingredients  

Clomipramine hydrochloride. 

How to Use 

Recommended-Dosage Chart  

Dog Weight (lbs) 

Clomicalm Per Day 

No. Tablets Per Day 

Tablet Strength 

2.75–5.5 

5 mg 

5 mg 

5.6–10.9 

10 mg 

5 mg 

11–22 

20 mg 

20 mg 

22.1–44 

40 mg 

40 mg 

44.1–88 

80 mg 

80 mg 

88.1–176 

160 mg 

80 mg 

Dosage & Administration Instructions  

  • Weight-Based Dosing: Administer the recommended daily dose of 2 to 4 mg/ kg body weight as prescribed by the veterinarian.
  • Flexible Schedule: Give medication once daily or divide into two doses depending on patient response and tolerance.
  • With Food Option: Provide tablets with a small amount of food to help reduce vomiting risk in sensitive dogs.
  • Behavior Program Required: Use alongside structured behavioral modification techniques, including desensitization and counterconditioning for optimal treatment success.
  • Veterinary Prescription Only: This medication is restricted for use by or on the order of a licensed veterinarian.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet. 

Additional Information 

Precautions  

  • Correct Diagnosis Essential: Conduct thorough physical examination and behavioral assessment to rule out non-anxiety causes before initiating treatment.
  • Seizure Risk Patients: Avoid use in dogs with a seizure history or medications that lower seizure threshold due to increased risk.
  • Medical Conditions Caution: Use carefully in dogs with cardiovascular disease, glaucoma, urinary retention, gastrointestinal motility disorders, or liver disease.
  • Breeding Restrictions: Do not administer to male breeding dogs due to the risk of testicular hypoplasia observed in studies.
  • Drug Interaction Awareness: Avoid combination with monoamine oxidase inhibitors and use caution with other CNS-active medications.

Possible Side Effects  

  • Gastrointestinal Upset: Some dogs may experience vomiting, diarrhea, decreased appetite, or increased thirst during treatment.
  • Lethargy Signs: You might notice reduced activity, drowsiness, or depression, especially at the beginning of treatment or when adjusting doses.
  • Neurological Effects: Rare instances of tremors, seizures, or coordination issues during treatment or overdose have been reported. 
  • Behavioral Changes: Occasionally, dogs may show aggression or changes in behavior toward people or other animals during therapy.
  • Liver Concerns: Increased liver enzymes or liver disease has been noted, particularly in dogs with existing health issues.

Storage Information  

  • Room Temperature Storage: Store tablets in a dry place at controlled temperature between 59°F and 77°F (15°C to 25°C).
  • Original Container: Keep unused tablets in the original closed container to maintain product stability and safety.
  • Child Safety: Keep medication out of reach of children to prevent accidental ingestion and potential health risks.

Shipping & Return  

We offer ground, express, priority, and international delivery; see our shipping policy for details.  

For return instructions or product concerns, please refer to our detailed refund policy.   

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.    

Frequently Asked Questions 

Q1: What is Clomicalm used for in dogs? 

Ans: Clomicalm is prescribed to help manage separation anxiety in dogs older than six months when used with behavioral modification training. It helps reduce symptoms such as destructive behavior, excessive vocalization, salivation, and inappropriate elimination associated with anxiety when owners are absent. 

Q2: How long does Clomicalm take to work in dogs? 

Ans: Clinical studies showed some dogs experienced improvement within the first week when Clomicalm was combined with behavioral modification therapy. The rate of improvement was faster compared to behavioral training alone, although individual response times may vary depending on severity and consistency of training. 

Q3: Can Clomicalm be given with food? 

Ans: Yes, Clomicalm may be administered with a small amount of food. Mixing the medication with food can help reduce the likelihood of vomiting, which is one of the more commonly reported side effects during treatment in some dogs receiving clomipramine therapy. 

Q4: Is Clomicalm safe for long-term use in dogs? 

Ans: The effectiveness and safety of Clomicalm for long-term use past twelve weeks have not been fully studied. Veterinarians decide how long to treat based on the patient's response, tolerance, and ongoing behavioral progress, with periodic reassessment recommended throughout therapy. 

Q5: Do I need a prescription to buy Clomicalm? 

Ans: Yes, Clomicalm is a prescription veterinary medication restricted for use by or on the order of a licensed veterinarian under federal law in the United States. Pet owners must obtain veterinary authorization before purchasing or administering this medication to their dog.