Zycortal 25mg/ml Suspension (4ml)

Desoxycorticosterone Therapy for Dogs with Addison’s Disease

Product Description

Zycortal Suspension is a long-lasting injectable mineralocorticoid made for dogs suffering from primary hypoadrenocorticism, commonly referred to as Addison’s disease. It provides necessary mineralocorticoid hormones to help maintain electrolyte balance and hydration. Given subcutaneously and adjusted based on each dog's reaction, Zycortal aids in keeping sodium and potassium levels normal, promoting overall health, energy, and quality of life.

Benefits

• Mineralocorticoid Replacement: Helps maintain optimal sodium and potassium balance for dogs with Addison’s disease.
• Extended Duration: Keeps electrolyte balance with doses usually given every 20 to 46 days.
• Personalized Dosing: Enables customized treatment according to clinical indicators and Na+/K+ levels for the best results.
• Under-the-Skin Injection: Easy injection beneath the skin, minimizing stress compared to taking oral medications.
• Proven Effectiveness: Field studies show over 86 percent of dogs remain clinically normal with proper dosing.
• Supports Quality of Life: Helps prevent lethargy, dehydration, and other Addisonian symptoms.

Ingredients

Active Ingredient

Desoxycorticosterone pivalate – 25 mg/mL

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Shake Well: Resuspend the product thoroughly before each use to ensure consistent dosing.
• Concurrent Therapy: Dogs with combined glucocorticoid deficiency should receive prednisone or prednisolone along with Zycortal Suspension.
• Monitor Electrolytes: Adjust doses based on sodium and potassium levels and clinical response.
• Long-Term Use: Dose intervals and amounts should be individualized to maintain normal electrolyte balance.
• Prescription Requirement: Zycortal Suspension is available by veterinarian prescription only and must be administered under veterinary guidance.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Cardiac Caution: Use with caution in dogs suffering from congestive heart disease or fluid retention to avoid complications.
• Renal Precaution: Due to the electrolyte and fluid shift, dogs with severe kidney disease may require careful monitoring during the course of treatment.
• Hepatic Caution: Exercise caution in dogs with primary liver failure due to potential effects on metabolism.
• Pregnancy Restriction: Its not recommended to be used on expecting dogs as the safety has not been established for the same.

Possible Side Effects

• Polyuria & Polydipsia: During the initial treatment phase, dogs may experience more urination and thirst.
• Gastrointestinal Issues: Vomiting or diarrhea has been reported in some dogs receiving Zycortal Suspension.
• Lethargy: Dogs may experience temporary depression or reduced activity during dose adjustments.
• Injection Reactions: Pain, redness, or swelling at the injection site can occur after administration.

Storage Information

• Room Temperature: Maintain a controlled room temperature of 25°C (77°F), with acceptable variations from 15–30°C.
• Do Not Freeze: Freezing can damage the suspension and decrease its effectiveness.
• Shelf-Life After Opening: Use within 120 days after the first puncture to keep stability and potency intact.
• Secure Storage: Keep out of reach of children and unauthorized persons to prevent accidental exposure.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: How is Zycortal Suspension administered to dogs?

Ans: Zycortal Suspension is given via a subcutaneous injection under the skin. The dosage and frequency are customized according to your dog's weight, clinical signs, and sodium/potassium levels. Always follow your veterinarian's recommendations for safe administration.

Q2: What is the recommended dose for my dog?

Ans: The first dose is 2.2 mg/kg based on body weight. The following doses are changed depending on the clinical response and the ratios of serum sodium to potassium. Continuous monitoring is essential to ensure the proper dosage and to maintain electrolyte balance.

Q3: Can Zycortal be used with other medications?

Ans: Dogs that have a combined glucocorticoid deficiency can be given prednisone or prednisolone with Zycortal. Do not use potassium-sparing diuretics at the same time, as they might lessen its effectiveness. Always check with your veterinarian before mixing treatments.

Q4: What side effects should I watch for?

Ans: Increased urination due to increased thirst, vomiting, diarrhea, lethargy, and injection site reactions are common side effects. Most of these effects are not serious, but if you experience severe or lasting symptoms, consult your veterinarian.

Q5: How should I store Zycortal Suspension?

Ans: Store at room temperature between 15–30°C (59–86°F) and do not freeze. Use within 120 days of first puncture and keep it out of reach of children or pets.