Percorten-V Injection for Dogs (Desoxycorticosterone Pivalate)

Long-Acting Addison’s Disease Support Injection for Dogs

Product Description

Percorten-V is a prescription injectable treatment used by veterinarians to manage primary adrenocortical insufficiency in dogs. It contains a long-acting form of desoxycorticosterone pivalate that helps bring electrolytes back into balance, maintain proper hydration, and support normal body function with convenient dosing schedules. It is typically used together with glucocorticoids and offers consistent hormone replacement therapy for dogs living with Addison’s disease, under a veterinarian’s guidance.

Please note that the product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

Benefits

• Electrolyte Balance: Helps normalize sodium and potassium levels by replacing deficient mineralocorticoid hormones in dogs with Addison’s disease.
• Long-Acting Formula: This microcrystalline depot formulation releases the hormone slowly over time, allowing for convenient dosing about every 25 days for many dogs.
• Supports Hydration: Helps maintain proper fluid balance and healthy blood volume, which are often affected in dogs with adrenal insufficiency.
• Proven Clinical Use: Demonstrated effectiveness in clinical studies for managing mineralocorticoid deficiency associated with canine primary adrenocortical insufficiency.

Ingredients

Active Ingredients

Desoxycorticosterone pivalate (DOCP) 25 mg/mL

Inactive Ingredients

Carboxymethylcellulose sodium, Polysorbate 80, Sodium chloride, Benzyl alcohol, Water for injection

How to Use

Recommended Dosage Chart

Dosage & Administration Instructions

• Veterinary Prescription: This medication requires a valid veterinary prescription and should only be administered under professional veterinary supervision.
• Intramuscular Injection: Give by intramuscular injection using sterile technique to ensure accurate dosing and reduce the risk of contamination.
• Individualized Dosing: The dose and timing may need to be adjusted based on electrolyte levels and how each dog responds to treatment.
• Concurrent Therapy: Most dogs will also need a glucocorticoid, such as prednisone, to properly manage adrenal hormone deficiencies.
• Regular Monitoring: Routine blood tests to check serum electrolytes are recommended to confirm the treatment is working and to help prevent dosing issues.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Preexisting Conditions: Use cautiously in dogs with congestive heart failure, severe renal disease, or conditions associated with edema or fluid retention.
• Drug Interactions: Use care when giving this medication with potassium-sparing diuretics, ACE inhibitors, or other drugs that can affect electrolyte levels.
• Electrolyte Monitoring: Sodium and potassium levels should be checked regularly to help prevent overdosing or an inadequate treatment response.
• Glucocorticoid Requirement: Failure to administer adequate glucocorticoid therapy may result in incomplete treatment of adrenal insufficiency symptoms.

Possible Side Effects

• Increased Thirst: Polyuria and polydipsia may occur due to mineralocorticoid effects on fluid and electrolyte regulation.
• Digestive Upset: Vomiting, diarrhea, or reduced appetite have been reported during treatment in some dogs.
• Behaviour Changes: Depression, lethargy, or weakness may occur, especially if an electrolyte imbalance develops during therapy.
• Injection Reactions: Local injection site discomfort or swelling may occur following intramuscular administration.

Storage Information

• Room Temperature: Store at controlled room temperature around 25°C with permitted excursions between 15°C and 30°C.
• Protect From Light: Keep the vial protected from light exposure to maintain product stability and effectiveness.
• Do Not Freeze: Avoid freezing the suspension, as freezing may affect formulation stability and therapeutic performance.
• Post-Puncture Use: Use the vial within four months after the first puncture to ensure sterility and product potency.

Shipping & Return  

We offer ground, express, priority, and international delivery; see our shipping policy for details.  

For return instructions or product concerns, please refer to our detailed refund policy.   

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.   

Frequently Asked Questions

Q1: What is Percorten-V used for in dogs?

Ans: Percorten-V is used as replacement therapy for mineralocorticoid deficiency in dogs diagnosed with primary adrenocortical insufficiency, also known as Addison’s disease. It helps restore electrolyte balance and maintain proper hydration and physiological function when administered under veterinary supervision.

Q2: How often does Percorten-V need to be administered?

Ans: The typical starting dose is 2.2 mg per kilogram of body weight given by intramuscular injection approximately every 25 days. However, dosing intervals may vary depending on the dog’s clinical response and electrolyte monitoring results determined by a veterinarian.

Q3: Does Percorten-V replace all adrenal hormones in dogs?

Ans: No, Percorten-V replaces only mineralocorticoid hormones. Dogs with Addison’s disease usually also require glucocorticoid supplementation, such as prednisone, because Percorten-V does not provide the glucocorticoid activity needed to fully manage adrenal insufficiency.

Q4: Are there any side effects associated with Percorten-V?

Ans: Possible side effects include increased thirst and urination, digestive upset such as vomiting or diarrhea, lethargy, and injection site reactions. These effects are often related to electrolyte changes or dosage adjustments and should be monitored by a veterinarian.

Q5: How should Percorten-V be stored after opening?

Ans: Percorten-V should be stored at controlled room temperature around 25°C with permitted excursions between 15°C and 30°C. The vial must be protected from light, not frozen, and used within four months after the first puncture to maintain sterility and potency.