Advantage II Flea Control for Extra Large Dogs (Over 55 lbs) Blue Box

Comprehensive Flea Prevention and Treatment for Dogs

Product Description

Advantage II for extra-large dogs provides fast, effective protection against fleas, flea larvae, flea eggs, and lice, and prevents re-infestation. It is waterproof and easy to apply, supporting healthy skin and coat while keeping your dog comfortable and flea-free for up to 30 days. It begins killing adult fleas within 12 hours and also helps treat and control chewing lice infestations effectively. 

Benefits

• Flea Protection: Provides effective flea control for dogs over 55 pounds.
• Easy Application: Monthly topical treatment is simple to apply, making flea prevention stress-free for pet owners.
• Total Flea Control: Kills adult fleas, flea larvae, and flea eggs through direct contact quickly and effectively.
• Fast-Acting Formula: Begins killing fleas the same day and continues protecting your dog for 30 days.
• Waterproof & Fragrance-Free: Topical formula is waterproof after 24 hours and free from fragrances for added convenience.
• Vet-Recommended Solution: Trusted by veterinarians, it ensures simple, monthly protection against fleas without prescriptions or oral medications.

Variants

• Small Dogs: 3–10 lbs
• Medium Dogs: 11–20 lbs
• Large Dogs: 21–55 lbs
• Extra Large Dogs: Over 55 lbs

Ingredients

Active Ingredients

Imidacloprid and Pyriproxyfen. 

Composition Table 

How to Use

Directions for Use

• Opening the Tube: Ensure the tube is at the pouch’s bottom. Use scissors to cut across the pouch top carefully.
• Selecting the Correct Product: Choose the appropriate Advantage II formula based on your dog’s weight category before applying the treatment.
• Preparing for Application: Bathe your dog prior to application and ensure they remain dry for 24 hours afterward.
• Applying the Treatment for Small Dogs (3–10 lbs): Hold the tube upright, remove the cap, and apply the contents directly to the skin between the shoulder blades.
• Applying for Medium to Extra-Large Dogs (11–20, 21–55 lbs, and over 55): Part the fur in several spots along the back, applying evenly from the shoulder blades to the tail.
• After Application and Disposal: Discard the empty tube safely, and do not reuse it. Repeat treatment monthly or as the veterinarian recommends.

Additional Information

Precautions

• General Safety Warning: Keep product out of children’s reach. Use cautiously to prevent accidental swallowing or contact incidents.
• Avoid Human Exposure: Avoid contact with eyes, skin, or clothing. Wash thoroughly after handling and before eating food.
• Application on Puppies: Do not use on puppies younger than 7 weeks old or weighing less than recommended.
• Species Restriction: Use only on dogs. Never apply this product to cats or other household animals.
• Sensitive or Sick Dogs: Avoid use on debilitated, aged, pregnant, or nursing dogs unless directed by a veterinarian.
• Veterinary Consultation: If irritation, discomfort, or allergic reactions occur, consult a veterinarian immediately before further applications. 

Possible Side Effects

• Post-Application Monitoring: Monitor your dog closely after each application to identify any unusual reactions or discomfort signs.
• Skin Irritation Signs: Side effects may include redness, scratching, or visible skin irritation following product application.
• Discomfort Symptoms: Watch for signs of general discomfort such as itching, restlessness, or mild skin sensitivity.
• Gastrointestinal Reactions: Some dogs may experience vomiting, diarrhea, or mild stomach upset after receiving the treatment.
• Severe Side Effects: If lethargy or other concerning reactions appear, discontinue use immediately and consult your veterinarian.
• Veterinary Contact Information: For professional guidance regarding adverse effects, contact your veterinarian or call 1-800-422-9874 immediately. 

Storage and Disposal Instructions

• Prevent Contamination: Do not contaminate water, food, or feed by improper product storage, disposal, or handling procedures.
• Pesticide Storage: Keep in a cool, dry area that is inaccessible to both children and household pets.
• Container Handling: Use only nonrefillable containers; do not attempt to reuse or refill after initial product use.
• Empty Container Disposal: Place empty containers in household trash or offer them for recycling when local facilities permit.
• Partly Filled Container Disposal: Call your local waste agency or 1-800-422-9874 for detailed disposal instructions and guidance.
• Product Disposal Warning: Never pour unused pesticide product into indoor or outdoor drains to prevent environmental contamination.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: What are the active ingredients in Advantage II Extra Large Dog?

Ans: Advantage II Extra Large Dog contains imidacloprid (9.10%) and pyriproxyfen (0.46%), a combination that kills adult fleas and prevents the development of eggs and larvae, providing immediate knockdown and ongoing interruption of the flea lifecycle when applied monthly.

Q2: Who is Advantage II Extra Large Dog intended for?

Ans: Advantage II Extra Large Dog is formulated for dogs and puppies 7 weeks or older weighing over 55 pounds. Do not use on cats; follow label age and weight limits and consult a veterinarian for animals with health concerns.

Q3: How often should I apply Advantage II Extra Large Dog?

Ans: Apply Advantage II Extra Large Dog once every 30 days for continuous flea and lice protection. Maintain monthly applications to ensure residual activity and lifecycle control; consult your veterinarian for special circumstances or severe infestations.

Q4: How quickly does Advantage II Extra Large Dog start killing fleas?

Ans: Advantage II Extra Large Dog begins killing adult fleas rapidly after application, typically producing significant flea reduction within 12 hours. The pyriproxyfen component prevents eggs and larvae from developing, helping reduce reinfestation over time.

Q5: Can I bathe my dog after applying Advantage II Extra Large Dog?

Ans: Avoid bathing or shampooing the treated area for 24 hours after application to allow the product to absorb and become water-resistant. After 24 hours, normal water exposure generally will not significantly reduce monthly effectiveness.

Q6: Is Advantage II Extra Large Dog safe to use with other flea products?

Ans: Consult your veterinarian before combining Advantage II Extra Large Dog with other topical or systemic flea products. A veterinarian can advise on safe combinations to avoid overdosing or adverse interactions while optimizing immediate and long-term flea control.

Q7: What side effects might occur after using Advantage II Extra Large Dog?

Ans: Some dogs may experience mild, transient reactions such as localized hair loss, redness, itching at the application site, or temporary lethargy. Severe reactions are rare; discontinue use and contact your veterinarian if you notice any unusual or persistent signs.

Q8: How should I apply Advantage II Extra Large Dog correctly?

Ans: Part the hair at the base of the neck and apply the entire tube directly to the skin in one or two spots. Avoid contact with the treated area until it is dry, and follow the label's handling and disposal instructions.

Q9: Will Advantage II Extra Large Dog help prevent flea-transmitted tapeworms?

Ans: By killing fleas that can carry tapeworm larvae, Advantage II Extra Large Dog reduces the risk of flea-transmitted tapeworm infection. Routine deworming and veterinary guidance remain important for comprehensive parasite control and pet health.

Q10: Where can I find complete safety and usage information for the Advantage II Extra Large Dog?

Ans: Read the complete product label and package insert for dosage, precautions, first-aid, and storage details. Consult your veterinarian for personalized advice, especially for pregnant, nursing, elderly, or medically compromised dogs.