Allopurinol Tablets, 300mg

Uric Acid Reducer Tablets for Bladder Stones and Leishmaniasis in Dogs

Product Description

Allopurinol 300mg Tablets are a prescription xanthine oxidase inhibitor used by veterinarians to reduce uric acid production in adult dogs. It works by shutting down the enzyme that turns purines into uric acid, which keeps urate bladder and kidney stones from forming. It is also used alongside other medications to help manage canine leishmaniasis, a serious parasitic infection. Prescribed off-label for dogs, this medication should always be given with food and plenty of fresh water throughout treatment.

Benefits

• Urate Stone Prevention: Lowers uric acid levels in the urine, reducing the chance of recurrent urate bladder and kidney stones in susceptible dog breeds.
• Portosystemic Shunt Support: Particularly useful for breeds prone to blood flow irregularities that push uric acid higher and contribute to urate stone formation.
• Leishmaniasis Treatment: Given alongside other medications to help manage canine leishmaniasis, a serious parasitic infection on the rise in the eastern United States.
• Chemotherapy Uric Acid Control: Keeps uric acid from spiking dangerously in dogs going through cancer-related chemotherapy treatments.
• Scored Tablets for Easy Dosing: The scored 300mg tablet design makes splitting and adjusting doses for dogs of different sizes and weights straightforward.

Ingredients

Active Ingredients

Allopurinol

How to Use

Allopurinol 300mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Giving this tablet with food helps keep stomach discomfort at bay, and making sure your dog has fresh water available throughout the day is an important part of the routine. Tucking the tablet into a soft pill pocket or pill wrap treat is a simple way to get your dog to take their dose with their meal without any fuss.

Shop Pill Pockets for Dogs

Additional Information

Precautions

• Adult Dogs Only: Puppies, kittens, and cats should not receive this medication, as it is only appropriate for use in adult dogs.
• Xanthine Stone Risk: Some dogs on this medication long-term may develop xanthine bladder stones, making periodic monitoring and dietary management important.
• Caution in Liver and Kidney Disease: Dogs with liver or kidney impairment need careful management on this medication, as it may build up and cause adverse effects.
• Avoid in Pregnancy: Pregnant or nursing animals should only receive this medication when a veterinarian has reviewed the situation and confirmed it is needed.
• Known Allergy Caution: Dogs with a known sensitivity or allergy to allopurinol should not be given this medication under any circumstances.
• Drug Interaction Risk: Share a full list of your dog's current medications, including azathioprine, mercaptopurine, warfarin, furosemide, and ammonium chloride, with your veterinarian before starting.
• Give With Food and Water: Pairing each dose with a meal and keeping fresh water available throughout the day helps reduce side effects and supports kidney health.

Possible Side Effects

• Drowsiness: Some dogs on allopurinol experience mild sedation and tiredness, particularly in the earlier stages of treatment.
• Digestive Upset: Nausea, vomiting, and diarrhea can come up, most often when the medication is given on an empty stomach or when treatment first starts.
• Skin Reactions: Skin rashes and eye irritation have been noted in some dogs and should be flagged to a veterinarian if they show up during treatment.
• Xanthine Bladder Stones: Ongoing use can lead to xanthine stone formation in the bladder or kidneys, which needs veterinary monitoring over the course of treatment.
• Serious Allergic Reactions: Trouble breathing, facial swelling, hives, blood in the urine, or painful urination point to a serious reaction needing immediate emergency veterinary care.

Storage Information

• Room Temperature: Tablets do best at room temperature inside a tightly closed container, kept away from heat and humidity.
• Protect From Moisture and Light: Direct sunlight and damp conditions can chip away at the tablet's potency, so a dry, shaded storage spot works best.
• Out of Reach: Keep this medication somewhere children and untreated animals in the home cannot get to it.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What conditions does allopurinol treat in dogs?

Ans: Allopurinol is prescribed to prevent recurrent urate bladder and kidney stones in adult dogs, especially breeds with portosystemic blood flow irregularities. It is also part of treatment plans for canine leishmaniasis and is used to keep uric acid under control in dogs undergoing cancer chemotherapy.

Q2: Why can allopurinol not be used in cats or puppies?

Ans: This medication is only appropriate for adult dogs. Cats process purines differently and face a much higher risk of serious adverse effects from allopurinol. Puppies are also not suitable candidates given the potential impact on organ systems that are still developing at that stage.

Q3: What are xanthine stones and why do they occur with allopurinol use?

Ans: Xanthine stones are an uncommon type of bladder or kidney stone that can develop in dogs on long-term allopurinol. Since the medication blocks the step where xanthine converts to uric acid, xanthine builds up instead and can crystallize over time. A veterinarian will check for this with periodic urine tests and imaging during extended treatment.

Q4: Does allopurinol interact with other common dog medications?

Ans: Allopurinol can significantly raise the toxicity of azathioprine and mercaptopurine by slowing how the body breaks them down. Warfarin and furosemide are also affected. Give your veterinarian a complete picture of every medication, supplement, and vitamin your dog is on before starting allopurinol.

Q5: How should allopurinol tablets be given to dogs to reduce side effects?

Ans: Giving allopurinol with a proper meal goes a long way toward reducing nausea and stomach discomfort. Keeping fresh water available all day is equally important, since good hydration takes pressure off the kidneys and helps lower the chance of stone formation throughout the course of treatment.