Cystorelin Sterile Solution (Gonadorelin Diacetate Tetrahydrate)

Effective Reproductive Support for Dairy and Beef Cattle

Product Description

CYSTORELIN® (gonadorelin injection) is a prescription veterinary solution designed to support reproductive health in dairy and beef cattle. It is used for the treatment of ovarian follicular cysts and is used with cloprostenol sodium to synchronize estrous cycles for fixed-time artificial insemination. By stimulating natural hormone release it promotes ovulation and improves breeding efficiency in managed herds.

Benefits

• Hormonal Activation: Encourages the release of key reproductive hormones like luteinizing hormone and follicle-stimulating hormone to support normal cycling.
• Cyst Management: Helps in resolving ovarian follicular cysts by triggering ovulation and promoting proper luteinization in cattle.
• Fertility Support: Contributes to higher conception rates when incorporated into fixed-time artificial insemination protocols with cloprostenol.
• Administration Flexibility: Suitable for both intramuscular and intravenous use allowing veterinarians to tailor treatment approaches.
• No Withdrawal Requirement: Does not require milk discard or withdrawal period when administered as per labeled veterinary guidelines.

Variants

30 ml vial

50 ml vial

Ingredients

Composition Table

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Initial Injection: Administer the first 2 ml dose at the start of the synchronization protocol to initiate the hormonal response.
• Follow-Up Protocol: Administer cloprostenol injection 6 to 8 days after the first dose to regulate estrous cycle timing.
• Second Dose Timing: Give the second CYSTORELIN dose 30 to 72 hours after cloprostenol administration for optimal synchronization.
• Insemination Window: Perform fixed-time artificial insemination within 0 to 24 hours following the second gonadorelin injection.
• Veterinary Supervision: This prescription product must be used under the direction of a licensed veterinarian as per federal regulations.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Human Safety: This is for animal use only and should be handled with care to avoid accidental exposure to humans.
• Keep Away Children: Keep it securely stored and out of children’s reach to avoid unintended contact or ingestion.
• Veterinary Oversight: Always check with the veterinarian for proper diagnosis, dosing, and reproductive management results.

Possible Side Effects

• Minimal Health Concerns: Shows no detectable increase in health issues when compared with animals receiving placebo treatments during research.
• Proven Safety Profile: Product has a high margin of safety across multiple species, with no meaningful impact on clinical markers or physiological well‑being.
• Injection Site Tolerance: Animals exhibited no notable irritation or negative reactions at the injection site when administered as per the veterinarian's guidance.

Storage Information

• Temperature Control: Store at or below 25°C (77°F) temperature to maintain product stability and effectiveness over time.
• Short Excursions: Short-term exposure up to 30°C (86°F) is permitted without compromising product integrity.
• Post-Opening Use: Use within six months after first vial puncture to ensure safety and therapeutic effectiveness.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.  

Frequently Asked Questions

Q1: What is CYSTORELIN used for in cattle?

Ans: CYSTORELIN is used for the treatment of ovarian follicular cysts in milk-producing cattle and to synchronize estrous cycles in both lactating and beef cows. It supports fixed-time artificial insemination programs by stimulating hormone release that leads to ovulation and improved reproductive efficiency in managed herds.

Q2: How does CYSTORELIN work in cattle reproduction?

Ans: CYSTORELIN contains gonadorelin which is a synthetic hormone that functions similarly to the body’s natural GnRH produced in the hypothalamus. It acts on the anterior pituitary to trigger the release of important reproductive hormones such as luteinizing hormone and follicle-stimulating hormone, supporting ovulation and maintaining regular reproductive function in cattle when used under veterinary guidance.

Q3: What is the recommended dosage of CYSTORELIN?

Ans: The recommended dose is 2 ml per cow, providing 100 mcg of gonadorelin diacetate tetrahydrate. It may be given either intramuscularly or intravenously for treating cystic ovaries, and intramuscularly when used within estrus synchronization programs under veterinary guidance.

Q4: Is there a withdrawal period for milk or meat after using CYSTORELIN?

Ans: There is no withdrawal period or milk discard time required when CYSTORELIN is used under veterinary supervision. This allows continued milk production and meat use without interruption, making it suitable for use in commercial dairy and beef cattle operations.

Q5: Is CYSTORELIN safe for use in cattle?

Ans: CYSTORELIN is safe for use in cattle. Research shows no major increase in health issues or negative effects on physiological parameters. It is overall well-tolerated when used according to the veterinary guidelines.

Clinical Research

https://www.proquest.com/openview/2029a66e8f565f59d2b0e615503652f9/1?pq-origsite=gscholar&cbl=18750

https://bovine-ojs-tamu.tdl.org/bovine/article/view/124