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Simparica for Dogs 44.1-88 lbs
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Simparica for Dogs 44.1-88 lbs

Zoetis SKU: 10012455-1

Prescription RequiredThis product requires veterinarian approval. Prescription details will be collected at Cart.

$28.60

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Size: 1 Chewable Tablet (1 month supply)
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Simparica 80mg Monthly Chewable for Flea and Tick Control in Large Dogs

Product Description

Simparica (sarolaner) 80 mg is a prescription-strength monthly chewable tablet formulated for dogs weighing 44.1 to 88 lbs. It kills adult fleas, treats and prevents flea infestations, and controls six species of ticks, including those that may carry Lyme disease. Each pork liver-flavored chew starts working within hours and delivers a full 35 days of parasite protection.

Benefits

  • Fast-Acting Flea Kill: Begins killing fleas within 3 hours of administration, reducing live flea counts by over 96% within 8 hours.
  • 35 Days of Protection: Provides continuous flea and tick control for up to 35 days with a single monthly chew.
  • Kills 6 Tick Species: Controls Lone Star, Gulf Coast, American Dog, Black-legged, Brown Dog, and Asian Longhorned ticks effectively.
  • Prevents Lyme Disease: FDA-approved to block Borrelia burgdorferi infections by killing Ixodes scapularis (deer) ticks before transmission.
  • Stops Flea Egg Production: Targets fleas before eggs ever get a chance to form, cutting off the flea life cycle and keeping re-infestation at bay.
  • Palatable Chewable Format: Pork liver-flavored tablet that can be given by hand, with food, or like a regular tablet.

Ingredients

Active Ingredients

Sarolaner 80 mg per tablet

How to Use

Dosage & Administration Instructions

  • Prescription Required: Simparica is a prescription-only medication; always obtain a valid veterinary prescription before administering to your dog.
  • Monthly Oral Dose: Give one 80 mg chewable tablet orally once every 28 to 30 days to dogs weighing 44.1 to 88 lbs.
  • Flexible Administration: Offer the tablet by hand, mixed into food, or administered like a regular oral tablet as per your preference.
  • Ensure Full Dose Consumed: Watch your dog for a few minutes after dosing to confirm the entire chew has been swallowed and not dropped.
  • Missed Dose: On a missed dose, give Simparica right away and simply pick up the regular monthly routine from there.
  • Year-Round Use: Keep it going every month throughout the year for protection that never lapses.
  • Treat All Pets: To reduce the chance of flea re-infestation, treat all dogs and cats in the household with an approved flea control product.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

  • Not for Young Puppies: Simparica is only suitable for dogs that are at least 6 months old; puppies younger than this should not receive this medication.
  • Seizure History Caution: Use with caution in dogs that have a prior history of seizures or any underlying neurological condition.
  • Breeding Dogs Excluded: Safety has not been evaluated in breeding, pregnant, or lactating dogs; consult your vet before use.
  • Dogs Only: Simparica is formulated only for dogs; never use this product in cats or other pets.
  • Secure Storage Required: Keep this product well out of reach of all pets at home to prevent accidental ingestion or overdose.
  • Keep Away from Children: Keep Simparica and all veterinary medications out of reach of children at all times.

Possible Side Effects

  • Vomiting: The most commonly reported adverse reaction; typically mild and transient in dogs receiving Simparica.
  • Diarrhea: Loose stools, occasionally with blood, have been reported in some dogs following administration of this medication.
  • Lethargy: Some dogs may appear tired or less active for a short period after receiving a dose of Simparica.
  • Neurological Signs: Tremors, ataxia, and seizures have been reported; contact your veterinarian immediately if any neurological signs appear.
  • Anorexia and Pruritus: Decreased appetite and skin itching are among the post-approval adverse events reported by dog owners and veterinarians.

Storage Information

  • Temperature Requirement: Store at or below 30°C (86°F); brief excursions up to 40°C (104°F) are permissible without affecting product quality.
  • Keep Away from Pets: Store in a secure area inaccessible to all animals to prevent accidental ingestion or unintended overdose.
  • Keep Away from Children: Always store this and all veterinary medications in a location children cannot access or reach.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What does the Simparica chewable tablet do for large dogs?

Ans: Simparica (sarolaner) is a monthly oral flea and tick treatment for dogs. It kills adult fleas, prevents re-infestation, and controls six tick species. It is also FDA-approved to help prevent Lyme disease infections in dogs 6 months and older.

Q2: How quickly does Simparica sarolaner start working on fleas?

Ans: Simparica begins killing fleas within 3 hours of the first dose. It reduces live flea numbers by over 96% within 8 hours of administration and maintains 100% flea-killing effectiveness for up to 35 days after each monthly dose.

Q3: Can I give Simparica flea chew with my dog's food?

Ans: Yes. Simparica can be offered by hand, placed in your dog's food, or given like a regular tablet. Since it is pork liver-flavored, most dogs accept it readily. Always ensure your dog consumes the full tablet to get complete protection.

Q4: Is the Simparica tick prevention chew safe for dogs with a seizure history?

Ans: Simparica belongs to the isoxazoline class, which has been associated with neurological signs including tremors, ataxia, and seizures in some dogs. Use with caution and only under veterinary guidance if your dog has a history of seizures or neurological disorders.

Q5: Which tick species does Simparica monthly tablet control?

Ans: Simparica controls six tick species: Lone Star tick, Gulf Coast tick, American Dog tick, Black-legged (deer) tick, Brown Dog tick, and Asian Longhorned tick. It is also FDA-approved to prevent Borrelia burgdorferi (Lyme disease) infections transmitted by deer ticks.

Clinical Research

Fleas - Centers for Disease Control and Prevention (CDC)

Ticks - Centers for Disease Control and Prevention (CDC)

Sarolaner - European Medicines Agency (EMA)