Simparica for Dogs 5.6-11 lbs

Simparica 10mg Purple Pack Monthly Chew for Flea and Tick Defense in Small Dogs

Product Description

Simparica (sarolaner) 10 mg is a prescription-strength, pork liver-flavored monthly chewable tablet designed for small dogs weighing 5.6 to 11 lbs. Each 8 mm brown square tablet, imprinted with "10," delivers the minimum recommended dose of 0.91 mg sarolaner per lb of body weight. Sarolaner targets parasites by shutting down the Gamma-Aminobutyric Acid (GABA) and glutamate-gated chloride channels in their nervous systems, throwing their neuromuscular activity into overdrive until they die off rapidly. From there, Simparica gets to work fast, with fleas dying off within 3 hours and ticks within 8 hours of a single dose, keeping protection solid and consistent right through all 35 days.

Benefits

• Fast Flea Kill in 3 Hours: Begins killing adult fleas within just 3 hours of the first dose, providing rapid relief for small dogs already experiencing active flea infestations.
• Tick Control in 8 Hours: Starts eliminating all six controlled tick species within 8 hours of administration, delivering fast-acting broad tick protection for small breeds.
• 35-Day Non-Diminishing Protection: Unlike products that lose potency toward month's end, Simparica maintains full flea and tick killing effectiveness through every one of its 35 days of coverage.
• Kills Six Tick Species: Controls Lone Star, Gulf Coast, American Dog, Black-legged, Brown Dog, and Asian Longhorned ticks, providing the widest tick coverage available in a single monthly chew.
• FDA-Approved Lyme Disease Prevention: Kills Black-legged (deer) ticks before Borrelia burgdorferi transmission can occur, offering an added layer of disease protection for small dogs.
• Breaks the Flea Life Cycle: Eliminates adult fleas before egg laying, helping prevent household flea re-infestation and reducing the overall environmental flea burden.
• 100% Satisfaction Guarantee on Prevention: Simparica comes backed by a manufacturer satisfaction guarantee on prevention, reflecting the confidence Zoetis has in its performance.

Ingredients

Active Ingredients

Sarolaner 10 mg per tablet

How to Use

Dosage & Administration Instructions

• Prescription Required: Simparica is a federally restricted medication available only by or on the order of a licensed veterinarian; always have a valid prescription before dispensing or administering.
• Monthly Dose for Small Dogs: Give one 10 mg chewable tablet orally once every 28 to 30 days to dogs weighing between 5.6 and 11 lbs at the minimum dose of 0.91 mg sarolaner per lb.
• Administer With or Without Food: The chew can be given alongside a meal, tucked into food, or offered directly by hand; no food is required for proper absorption.
• Confirm Full Consumption: Monitor your small dog after dosing to ensure the entire 10 mg chewable has been fully swallowed and no portion has been left behind.
• Missed Dose: If a scheduled monthly dose is missed, administer it as soon as possible and then resume the regular monthly dosing schedule going forward.
• Year-Round Use Recommended: Treatment may begin at any time of year and should be continued monthly without interruption for consistent, reliable flea and tick protection.
• Treat All Household Pets: To minimize the risk of household flea re-infestation, treat all dogs and cats in the home with an appropriate veterinarian-approved flea control product.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Minimum Age Requirement: Simparica is approved for dogs 6 months of age and older only; it should never be administered to puppies younger than this regardless of body weight.
• Seizure and Neurological History: Use with caution in small dogs with a prior history of seizures or neurological conditions, and only under close veterinary supervision throughout treatment.
• Breeding, Pregnant, or Lactating Dogs: Safe use in breeding, pregnant, or nursing female dogs has not been established; consult your veterinarian before use in these animals.
• For Dogs Only: Simparica is formulated exclusively for dogs and must never be administered to cats, as stated clearly on the product label.
• Prevent Accidental Ingestion: Despite the pork liver flavor, store tablets in a fully secured location inaccessible to all pets to prevent accidental overdose.
• Keep Away from Children: As with all prescription veterinary medications, Simparica must always be stored completely out of reach of children.

Possible Side Effects

• Vomiting: The most frequently reported adverse reaction across clinical studies; typically mild, transient, and not requiring treatment discontinuation in most small dogs.
• Diarrhea: Loose or occasionally blood-tinged stools have been reported in some dogs following Simparica administration during clinical and post-approval studies.
• Lethargy: Some dogs may appear temporarily less active or fatigued for a brief period after receiving a monthly Simparica dose.
• Tremors and Ataxia: Post-approval reports include muscle tremors and unsteady movement; contact your veterinarian immediately if any neurological signs are observed after dosing.
• Seizures: Seizures have been reported in dogs treated with isoxazoline-class products, including those with no previous seizure history; immediate veterinary care is required if this occurs.
• Anorexia and Pruritus: Reduced appetite and skin itching are among the post-approval adverse events reported by dog owners and veterinarians following sarolaner administration.

Storage Information

• Store at or Below 30°C: Keep at or below 30°C (86°F); brief temperature excursions up to 40°C (104°F) are permissible without compromising the stability or efficacy of the product.
• Secure from All Pets: Store in a locked or inaccessible location where no animals can reach the tablets, preventing accidental self-administration or unintentional overdose.
• Keep Away from Children: Always store Simparica and all prescription pet medications in a location completely out of reach of children.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Simparica 10mg purple pack chewable used for in small dogs?

Ans: Simparica 10 mg is a monthly prescription flea and tick chewable for small dogs weighing 5.6 to 11 lbs. It kills adult fleas, prevents flea re-infestation, controls six tick species, and is FDA-approved to help prevent Lyme disease by eliminating Black-legged ticks before disease transmission occurs.

Q2: How does Simparica sarolaner chewable protect small dogs from ticks and fleas?

Ans: Sarolaner blocks GABA and glutamate-gated chloride channels in the parasite's nervous system, triggering uncontrolled neuromuscular activity that leads to rapid paralysis and death. Because it acts through the bloodstream after parasites bite and feed, it works systemically and is not affected by bathing or rain.

Q3: Is Simparica flea and tick chew safe for small dogs under one year old?

Ans: Simparica is approved for dogs 6 months of age and older. It is not recommended for puppies younger than 6 months, regardless of weight. If your small dog is between 6 months and one year of age, consult your veterinarian before starting any flea and tick prevention program.

Q4: Does Simparica 10mg monthly tablet remain effective toward the end of the protection period?

Ans: Yes. Unlike some flea and tick treatments that lose potency as the month progresses, Simparica delivers consistent, non-diminishing protection across its full 35-day period. This means your small dog is equally protected on day 35 as on day one of the dosing cycle.

Q5: Can Simparica small dog chewable tablet help with flea allergy dermatitis?

Ans: Yes. By killing adult fleas rapidly before they lay eggs and maintaining continuous flea control throughout the month, Simparica helps reduce the flea exposure that triggers allergic skin reactions. Dogs experiencing flea allergy dermatitis may see improvement in associated signs such as itching, skin redness, and hair loss with consistent monthly use.

Clinical Research

• American Veterinary Medical Association (AVMA) – Flea and Tick Control in Pets
• FDA – Safe Use of Isoxazoline Flea and Tick Products
• Companion Animal Parasite Council (CAPC) – Tick-Borne Diseases in Dogs