Simparica for Dogs 22.1-44 lbs

Simparica 40mg Monthly Chewable for Flea and Tick Control in Medium Dogs

Product Description

Simparica (sarolaner) 40 mg is a prescription-strength, pork liver-flavored monthly chewable tablet designed for medium-sized dogs weighing 22.1 to 44 lbs. Its active ingredient, sarolaner, targets the nervous system of fleas and ticks by blocking GABA and glutamate receptors, causing paralysis and death in parasites. It begins killing fleas within 3 hours and ticks within 8 hours, offering dependable 35-day protection.

Benefits

• Kills Fleas Within Hours: One oral dose gets to work fast, with adult fleas dying off within 3 hours and ticks within 8 hours.
• Uninterrupted Monthly Coverage: Each dose keeps flea and tick protection going strong and steady for a full 35 days without any drop-off.
• Controls Six Tick Species: A single monthly chew covers Lone Star, Gulf Coast, American Dog, Black-legged, Brown Dog, and Asian Longhorned ticks.
• Lyme Disease Prevention: FDA-approved to help prevent Borrelia burgdorferi infections by killing deer ticks before disease transmission can occur.
• Breaks the Flea Life Cycle: Works at the source by stopping adult fleas from ever reaching the egg-laying stage, clearing active infestations and keeping fresh ones from gaining ground.
• Relieves Flea Allergy Symptoms: Helps reduce dermatitis-related signs such as erythema, papules, alopecia, and pruritus caused directly by flea infestations.
• Weight-Specific Blue Pack: The blue color-coded pack ensures accurate, safe dosing specifically calibrated for medium dogs in the 22.1 to 44 lb range.

Ingredients

Active Ingredients

Sarolaner 40 mg per tablet

How to Use

Dosage & Administration Instructions

• Prescription Needed: Simparica is a federally restricted prescription medication; a valid veterinary prescription is required before dispensing or administering this product.
• Correct Dose for Medium Dogs: Give one 40 mg chewable tablet orally once every 28 to 30 days to dogs weighing between 22.1 and 44 lbs.
• Multiple Ways to Administer: The chew can be offered directly by hand, tucked into food, or given as a regular oral tablet based on what your dog accepts easily.
• Confirm Full Consumption: Monitor your dog for a few minutes after dosing to make sure the entire chewable tablet has been fully swallowed.
• Missed Dose Management: If a monthly dose is skipped, give it as soon as you remember and then continue with the regular monthly dosing schedule.
• Year-Round Administration: Treatment can start at any time of year and should be continued monthly without interruption for consistent, reliable coverage.
• Treat All Household Pets: For best results against re-infestation, treat all dogs and cats in the home with a vet-approved flea and tick control product.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Age Restriction Applies: Simparica is only approved for dogs aged 6 months and older; it should not be administered to younger puppies under any circumstance.
• Neurological History: Use with caution in any dog with a known history of seizures or neurological disorders, and only under direct veterinary supervision.
• Reproductive Safety Unknown: The product has not been evaluated in breeding, pregnant, or nursing dogs; consult your veterinarian before use in these animals.
• Dogs Only: Simparica is strictly formulated for use in dogs and must never be given to cats or any other animal species.
• Safe Storage is Essential: Keep the product in a secured location away from all pets to prevent accidental ingestion and potential overdose.
• Out of Children's Reach: As with all veterinary medications, Simparica must always be stored where children cannot access it.

Possible Side Effects

• Vomiting: Most commonly observed adverse reaction in clinical trials; typically mild, short-lived, and not a cause for immediate concern.
• Diarrhea: Loose or bloody stools have been reported in a small number of dogs following monthly Simparica administration.
• Lethargy: A dog may show temporary low energy or reduced activity in the period following administration of a dose.
• Tremors and Ataxia: Neurological signs such as muscle tremors and unsteady movement have been reported; contact your vet right away if observed.
• Seizures: Seizures have been reported in dogs on isoxazoline-class drugs, including those with no prior seizure history; veterinary attention is required immediately.
• Reduced Appetite and Itching: Anorexia and pruritus are among the post-approval adverse events noted from owner and veterinary reports after Simparica use.

Storage Information

• Store Below 30°C: Keep at or below 30°C (86°F); brief temperature excursions up to 40°C (104°F) are acceptable without compromising product integrity.
• Secure from Pets: Store in a locked or inaccessible location away from all pets to prevent accidental self-administration or overdose.
• Away from Children: Always store Simparica and all pet medications in a place that is completely out of the reach of children.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Simparica Blue Pack 40mg used for in medium dogs?

Ans: Simparica Blue Pack (40 mg) is a monthly prescription chewable that treats and prevents flea infestations and controls six tick species in medium dogs weighing 22.1 to 44 lbs. It is also FDA-approved to help prevent Lyme disease caused by deer tick bites.

Q2: How does sarolaner in Simparica kill fleas and ticks on dogs?

Ans: Sarolaner blocks GABA and glutamate neurotransmitter receptors in parasites, triggering uncontrolled neuromuscular activity that leads to paralysis and death. This mechanism acts through the dog's bloodstream when parasites feed, making it fast and highly effective.

Q3: Is Simparica flea tablet safe to use throughout the year for medium dogs?

Ans: Yes. Simparica can be started at any time of year and should be given monthly without interruption for continuous coverage. In areas where fleas and ticks are active year-round, consistent monthly dosing is recommended to maintain complete protection for your dog.

Q4: Does Simparica sarolaner chew help dogs suffering from flea allergy dermatitis?

Ans: Yes. By killing fleas before they lay eggs and eliminating active infestations, Simparica has been shown to improve dermatitis-related signs like skin redness, hair loss, papules, and intense itching that are directly caused by flea allergy reactions in dogs.

Q5: Why is weight-specific dosing important when choosing a Simparica pack for your dog?

Ans: Each Simparica pack is color-coded and calibrated to deliver the correct minimum dose of sarolaner per kilogram of body weight. Choosing the right pack, like the blue 40 mg for 22.1 to 44 lb dogs, ensures your dog receives safe, effective, and precisely targeted parasite protection every month.

Clinical Research

American Veterinary Medical Association (AVMA) - Flea and Tick Control in Pets

FDA - Safe Use of Isoxazoline Flea and Tick Products

Companion Animal Parasite Council (CAPC) - Tick-Borne Diseases in Dogs