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Simparica Trio Chewable Tablet for Dogs 88.1-132.0 lbs

$42.64

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Prescription Required

Zoetis SKU: 10022671

Size: 1 Chewable Tablet
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Comprehensive Monthly Parasite Protection for Extra-Large Dogs

Product Description

Simparica Trio for Dogs 88.1-132.0 lbs is a once-monthly, liver-flavored chewable providing three-in-one defense against fleas, ticks, and heartworm disease while treating roundworms and hookworms. Its fast-acting sarolaner, moxidectin, and pyrantel pamoate combination delivers broad-spectrum parasite control and convenient dosing in a single tasty tablet.

Ingredients

Active Ingredients

Sarolaner 56 mg, Moxidectin 1.12 mg, Pyrantel Pamoate 200 mg

Inactive Ingredients

Beef liver flavor, microcrystalline cellulose, silicon dioxide, magnesium stearate, other excipients

Variants/Types

Variants

Active Ingredients

Weight Range

Box Label Color

Sarolaner (mg)

Moxidectin (mg)

Pyrantel (mg)

2.8-5.5 lbs

Yellow

5 mg

0.1 mg

20 mg

5.6-11 lbs

Purple

10 mg

0.2 mg

50 mg

11.1-22 lbs

Orange

20 mg

0.4 mg

100 mg

22.1-44 lbs

Blue

40 mg

0.8 mg

200 mg

44.1-88 lbs

Green

48 mg

0.96 mg

200 mg

88.1-132 lbs

Brown

56 mg

1.12 mg

200 mg

How to Use

Dosage & Administration Instructions

  • Weight Confirmation: Verify the dog’s weight is between 88.1 and 132.0 lbs.
  • Monthly Dose: Administer one red tablet orally once every 30 days.
  • Food Optional: Give with or without food to reduce gastrointestinal upset.
  • Full Consumption: Ensure the entire chew is consumed for complete efficacy.
  • Consistent Schedule: Treat on the same calendar day each month to maintain protection.

Additional Information

Precautions

  • Neurological Conditions: Use with caution in dogs with a history of seizures or neurologic disorders.
  • Heartworm Testing: Confirm negative heartworm status before initiating treatment.
  • Pregnancy & Lactation: Safety not established in breeding, pregnant, or nursing dogs.
  • Drug Interactions: Inform the veterinarian of all concurrent medications before dosing.
  • Age Restriction: Safe for puppies and dogs 8 weeks or older of appropriate weight.

Possible Side Effects

  • Vomiting: Occasional mild vomiting may occur shortly after dosing.
  • Diarrhea: Soft stools or diarrhea can develop temporarily post-dose.
  • Lethargy: Temporary decreased energy levels reported in some dogs.

Benefits

  • Rapid Flea Control: Eliminates adult fleas within four hours of administration.
  • Effective Tick Kill: Kills five tick species within eight hours on contact.
  • Heartworm Prevention: Eliminates larval heartworms transmitted by mosquitoes.
  • Intestinal Worm Treatment: Controls roundworms and hookworms with a single chew.
  • Convenient Chewable: Liver-flavored tablet ensures high acceptance and compliance.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: How quickly does Simparica Trio eliminate fleas and ticks in extra-large dogs?

Ans: Simparica Trio kills adult fleas within 4 hours and five tick species within 8 hours following oral administration in dogs weighing 88.1-132.0 lbs. This rapid action helps stop parasite feeding and reduces the risk of vector-borne disease transmission effectively.

Q2: Can Simparica Trio be given with other parasite preventives or medications?

Ans: Yes, Simparica Trio can be safely administered alongside veterinarian-prescribed heartworm, tick, or mite preventives, vaccines, and antibiotics. Always inform your veterinarian of all current medications to avoid potential interactions or overlapping therapies.

Q3: What should I do if my extra-large dog misses its monthly Simparica Trio dose?

Ans: If a monthly dose is missed, administer Simparica Trio as soon as you remember and then resume the regular dosing schedule. Do not give two tablets on the same day to make up for the missed dose to minimize the risk of adverse reactions.

Q4: Is Simparica Trio suitable for dogs with neurological histories or seizure disorders?

Ans: Use caution when administering Simparica Trio to dogs with a history of seizures or neurological disorders. The isoxazoline ingredient sarolaner may induce neurologic signs in susceptible animals; consult your veterinarian before beginning treatment.

Q5: Do I need a heartworm test before starting Simparica Trio in extra-large dogs?

Ans: Yes, all dogs must test negative for heartworm infection before the first Simparica Trio dose. Treating an infected dog can cause severe reactions as the medication eliminates circulating microfilariae from the bloodstream.