Sporimune (Cyclosporine) USP Modified, 100mg (15 capsules)

Controls Atopic Dermatitis Symptoms in Dogs Effectively

Product Description

Sporimune (cyclosporine) USP Modified 100 mg capsules assist in managing atopic dermatitis in dogs by focusing on the immune response that triggers itching and skin inflammation. This therapy, suggested by veterinarians, produces a microemulsion for enhanced absorption, helps with ongoing allergy control, and permits dose tapering following clinical improvement, delivering a steroid-free remedy for chronic allergic skin conditions in dogs.

Benefits

• Targets Immune Response: Modifies T lymphocyte behaviour and interleukin-2 synthesis to mitigate allergic inflammation, prioritizing lasting solutions over temporary symptom relief.
• Controls Chronic Itching: Demonstrated in clinical trials to effectively lower pruritus and the intensity of skin lesions associated with canine atopic dermatitis.
• Steroid Free Therapy: Provides an alternative to corticosteroids or antihistamines for long-term allergy management in dogs.
• Flexible Dosing Schedule: After initial treatment, dosing frequency can often be reduced to every other day or twice weekly.
• Reliable Absorption: Modified microemulsion formulation enhances bioavailability and consistent drug absorption when administered orally.

Ingredients

Cyclosporine (USP Modified) 100 mg per capsule

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Veterinary Prescription Required: This medication is restricted to use by or on the order of a licensed veterinarian only.
• Initial Daily Dose: Administer 5 mg/kg once daily for 30 days before considering a gradual reduction in dosing frequency.
• Maintenance Adjustment: After improvement, dosing frequency may be reduced to every other day or twice weekly to maintain response.
• Meal Timing: Offer capsules at least an hour before or two hours post-feeding for maximum absorption.
• Missed Dose: If a dose is forgotten, give it as soon as possible, ensuring you do not go over the once-daily dosage.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Age Restrictions: Safety and effectiveness are not established in dogs younger than six months or weighing under four pounds.
• Breeding Safety: Not recommended for breeding, pregnant, or lactating dogs due to lack of safety data.
• Immune Suppression: Immunosuppressive action may increase susceptibility to infections or exacerbate preexisting neoplastic conditions.
• Diabetes Caution: May elevate blood glucose levels, so careful monitoring is advised in dogs with diabetes mellitus.
• Drug Interactions: Use cautiously with medications affecting cytochrome P450 enzymes, including azole antifungals like ketoconazole.

Possible Side Effects

• Gastrointestinal Symptoms: The side effects most often reported during treatment include vomiting and diarrhea.
• Gum Swelling: Gingival hyperplasia can happen, usually getting better after lowering the dose or changing the treatment.
• Lethargy & Appetite Loss: Some dogs may experience reduced appetite, lethargy, or decreased activity during therapy.
• Infection Risk: Increased susceptibility to infections such as otitis externa or urinary tract infections may develop.
• Neurological Events: Rare cases of tremors or seizures have been reported in dogs receiving cyclosporine therapy.

Storage Information

• Room Temperature Storage: Store capsules at a stable temperature of 68°F to 77°F (20°C to 25°C).
• Original Packaging: Keep medication in the original unit dose container to maintain stability and protection.
• Child Safety: Keep out of reach of children and other pets to prevent accidental ingestion.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.  

Frequently Asked Questions

Q1: What is Sporimune used for in dogs?

Ans: Sporimune is used to manage atopic dermatitis in dogs by lowering the immune responses that cause itching and skin inflammation. It aids in decreasing itching and skin problems linked to allergic dermatitis and is meant for dogs that weigh a minimum of 4 pounds, under the care of a veterinarian.

Q2: How long does Sporimune take to work in dogs?

Ans: Clinical research indicates that itching and skin severity scores improve within roughly four weeks of daily treatment. After the initial improvement, veterinarians might decrease the frequency of dosing to sustain the results, though the response time can differ based on the specific dog's condition and severity.

Q3: How should Sporimune be given to dogs?

Ans: Sporimune capsules should be administered orally at least one hour before or two hours after feeding. Capsules must not be opened or broken. The usual initial dose is 5 mg for each kilogram taken once a day for 30 days, then the frequency can be adjusted according to the clinical response.

Q4: Is Sporimune a steroid or an antihistamine?

Ans: Sporimune is neither a corticosteroid nor an antihistamine. It contains cyclosporine, an immunosuppressive agent that works by inhibiting T lymphocyte activation and interleukin-2 production, targeting the underlying immune cause of allergic dermatitis rather than only relieving symptoms temporarily.

Q5: What are the most common side effects of Sporimune?

Ans: The most commonly reported side effects include vomiting and diarrhea, especially during the early treatment period. Other possible reactions include lethargy, decreased appetite, gum enlargement, and infections. Many side effects improve with continued therapy or dose adjustments under veterinary guidance.