Vetameg (flunixin meglumine) Injection (50mg/mL)

Fast-Acting NSAID Injection for Pain and Inflammation in Horses and Cattle

Product Description

Vetameg (flunixin meglumine) Injection 50 mg/mL is a potent, non-narcotic, non-steroidal anti-inflammatory drug (NSAID) for use in horses and cattle. It delivers powerful analgesic, anti-inflammatory, and antipyretic effects by inhibiting prostaglandin production. Flunixin persists in inflammatory tissues, providing relief well beyond detectable plasma drug concentrations, making it a fast and effective choice for pain, fever, and inflammation management.

Benefits

• Potent Pain Relief: Flunixin is four times more potent than phenylbutazone on a mg-per-mg basis as measured by reduction in lameness and swelling in horses.
• Fast Onset of Action: For musculoskeletal disorders, activity begins within 2 hours, with peak response occurring between 12 and 16 hours post-administration.
• Rapid Colic Pain Relief: When given intravenously for equine colic, pain is alleviated in under 15 minutes in many cases, with effects lasting 24 to 36 hours.
• Prolonged Anti-Inflammatory Activity: Flunixin persists in inflamed tissues and continues providing anti-inflammatory effects well beyond the period of detectable plasma drug concentration.
• Multi-Indication Use: Effective for musculoskeletal pain, equine colic, bovine respiratory disease fever, acute mastitis, and inflammation associated with endotoxemia in cattle.
• Non-Narcotic Formula: Vetameg provides powerful analgesia without narcotic agents, making it a safer long-term anti-inflammatory and pain management option for livestock.

Variants

Vetameg (flunixin meglumine) Injection 50 mg/mL is available in the following sizes:

• 100 mL Multi-Dose Vial
• 250 mL Multi-Dose Vial

Ingredients

Composition Table

Other Ingredients

Hydrochloric acid, water for injection q.s.

How to Use

Dosage & Administration Instructions

• Veterinarian Authorization: Federal law limits this drug to veterinary use only; follow your veterinarian's specific instructions precisely before and during administration.
• Horses, Musculoskeletal Conditions: Administer 0.5 mg per pound body weight once daily via intravenous or intramuscular injection; treatment must not exceed 5 consecutive days.
• Horses, Colic Management: Give 0.5 mg per pound intravenously for rapid relief; repeat doses only when colic signs return and always identify and address the underlying cause.
• Cattle, Respiratory Disease and Endotoxemia: Administer 1.1 to 2.2 mg/kg once daily or in two divided doses 12 hours apart via slow intravenous injection for up to 3 days; daily dose must not exceed 2.2 mg/kg.
• Cattle, Acute Mastitis Treatment: Give a single intravenous dose of 2.2 mg/kg; rapid intravenous usage must be prohibited in all cattle under any circumstance.
• Intravenous Route in Cattle Only: Vetameg is approved for intravenous use exclusively in beef and dairy cattle; intramuscular administration in cattle is strictly prohibited.
• No Intra-Arterial Use in Horses: Intra-arterial injection must be strictly avoided in horses as accidental administration through this route triggers serious neurological and physical adverse reactions.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Renal and GI Risk Patients: Use with caution in animals that are dehydrated, on diuretic therapy, or have known renal, cardiovascular, or hepatic dysfunction, as these are at greatest risk for renal toxicity.
• Avoid Concurrent NSAID or Steroid Use: Concomitant use with other NSAIDs or corticosteroids should be avoided or closely monitored due to the risk of gastrointestinal ulceration.
• Not for Breeding Bulls: Do not use in bulls intended for breeding, as the reproductive effects of Vetameg have not been fully investigated in this class of cattle.
• Cattle Parturition Risk: Do not use within 48 hours of expected parturition in cattle, as flunixin may delay labor and prolong parturition, increasing the risk of stillbirth.
• Not for Veal Calves or Dry Dairy Cows: This product must not be used in dry dairy cows, veal calves, or preruminating calves, as a safe withdrawal period has not been established.
• Meat and Milk Withdrawal: Do not slaughter treated cattle for human consumption within 4 days of the last dose; discard all milk produced during treatment and for 36 hours after the final dose.
• Food Horse Restriction: Vetameg is not approved for use in horses that will be slaughtered for human food consumption.

Possible Side Effects

• Intra-Arterial Injection Reactions: Accidental intra-arterial administration in horses may cause ataxia, hyperventilation, and muscle weakness that typically resolve without treatment.
• Gastrointestinal Ulceration Risk: Like all NSAIDs, Vetameg can cause gastrointestinal ulceration, particularly at higher doses or when used over extended treatment periods. 
• Renal Toxicity Risk: Cyclo-oxygenase inhibitory NSAIDs, including flunixin meglumine, may be associated with renal toxicity, especially in vulnerable or compromised animals.
• Estrous Cycle Disruption in Cattle: Flunixin administered during the prostaglandin phase of the estrous cycle may cause a delay in the onset of estrus in cattle.

Storage Information

• Temperature Range: Store between 2°C and 30°C (36°F and 86°F) at all times to maintain product stability and efficacy.
• Protect from Light: Shield the vial from direct light exposure during storage to preserve the integrity of the solution.
• Use After First Puncture (100 mL): Once the 100 mL vial has been punctured, use the product within 60 days to ensure sterility and potency.
• Use After First Puncture (250 mL): The 250 mL vial should be used within 28 days of the first puncture and must not be punctured more than 30 times; use multi-dosing equipment if more punctures are expected.
• Keep Out of Reach: Store in a secure location completely out of reach of children and unauthorized persons at all times.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Vetameg (flunixin meglumine) injection used for in horses and cattle?

Ans: In horses, Vetameg is used to relieve pain and inflammation from musculoskeletal disorders and visceral pain from colic. In cattle, it controls fever from bovine respiratory disease, acute mastitis, and inflammation associated with endotoxemia. It requires a veterinary prescription.

Q2: How quickly does Vetameg flunixin injection start working in horses?

Ans: For musculoskeletal disorders, activity begins within 2 hours, with peak response between 12 and 16 hours and a duration of 24 to 36 hours. For equine colic when given intravenously, pain relief may occur in under 15 minutes in many cases.

Q3: Can Vetameg flunixin meglumine injection be given intramuscularly to cattle?

Ans: No. Vetameg is approved for intravenous use only in beef and dairy cattle. Intramuscular or intravenous administration is permitted in horses, but in cattle strictly intravenous administration must be used, and rapid IV injection should be avoided.

Q4: What is the meat and milk withdrawal time for Vetameg in cattle?

Ans: Cattle must not be slaughtered for human consumption within 4 days of the last Vetameg treatment. Milk collected during treatment and for 36 hours after the last dose must not be used for food. The product is not approved for use in veal calves.

Q5: Is Vetameg safe to use near calving time in cattle?

Ans: No. Vetameg must not be administered within 48 hours of expected parturition in cattle. Flunixin meglumine can delay labor and prolong parturition by inhibiting prostaglandins, which may increase the risk of stillbirth.

Q6: Can Vetameg injection be used alongside other anti-inflammatory medications?

Ans: Concurrent use of Vetameg with other NSAIDs or corticosteroids should be avoided or very closely monitored. Combining these drug classes increases the risk of serious gastrointestinal ulceration and other adverse effects. Always consult your veterinarian.

Q7: How long can the Vetameg multi-dose vial be used after it is first opened?

Ans: The 100 mL vial should be used within 60 days of first puncture. The 250 mL vial must be used within 28 days of first puncture and should not be punctured more than 30 times; multi-dosing equipment is recommended if more punctures are needed.