Tri-Heart Plus Chewable Tablet for Dogs up to 25lbs

Tri-Heart Plus for Dogs up to 25 lbs

Monthly Protection Against Heartworms and Intestinal Parasites

Tri-Heart Plus for Dogs up to 25 lbs is a veterinary-approved, chewable heartworm preventive designed to protect small dogs from heartworm disease, hookworms, and roundworms. Specially formulated for dogs weighing 1–25 pounds, this once-a-month flavored tablet contains a proven combination of Ivermectin and Pyrantel, offering broad-spectrum parasite protection in a palatable and easy-to-administer form.

Recommended by veterinarians across the U.S., Tri-Heart Plus is a cost-effective alternative to Heartgard Plus, providing the same active ingredients and protection level. Its beef-flavored chew makes administration easier, especially for picky eaters, and ensures that your dog stays protected year-round.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Also Available in Other Weight Ranges

Tri-Heart Plus is available in multiple weight-specific formulas to ensure accurate dosing and maximum parasite protection for dogs of all sizes:

• Tri-Heart Plus for Small Dogs – Up to 25 lbs : Perfect for small breeds and puppies needing gentle yet effective monthly protection. (You're currently viewing this product)
• Tri-Heart Plus for Medium Dogs – 26 to 50 lbs : ideal for medium-sized dogs. 
• Tri-Heart Plus for Large Dogs – 51 to 100 lbs : Designed for large breeds needing high-dosage, broad-spectrum worm prevention.

Choose the formula that matches your dog’s weight for consistent, vet-recommended parasite protection.

What Are the Benefits of Tri-Heart Plus for Small Dogs?

Tri-Heart Plus delivers comprehensive parasite control in a simple monthly dose, safeguarding your pet’s heart and digestive system.

• Prevents deadly heartworm disease caused by Dirofilaria immitis transmitted through mosquito bites
  
• Treats and controls intestinal worms, including adult Toxocara canis, Toxascaris leonina (roundworms), and Ancylostoma caninum, Uncinaria stenocephala (hookworms)
  
• Vet-recommended alternative to Heartgard Plus at a more affordable price
  
• Palatable chewable tablet for easy oral administration
  
• Safe for puppies as young as 6 weeks, weighing at least 1 pound
  
• Backed by FDA approval for trusted efficacy and safety
  

Dosage and Administration for Tri-Heart Plus (Dogs 1–25 lbs)

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

• Weight Range: For dogs 1–25 lbs
  
• Dosage: One chewable tablet every 30 days
  
• Administration: Can be given by hand or mixed with food. Ensure dog consumes entire dose.
  
• Start Early: Begin treatment at 6 weeks of age and continue monthly, year-round
  

Important Note: If a dose is missed by more than 30 days, consult your vet before resuming treatment.

When Should You Start Tri-Heart Plus?

• Start at 6 weeks of age
  
• Continue monthly, year-round
  
• Don’t skip a dose—even in winter
  
• Test for heartworms before starting if your dog has missed multiple months
  

Pro Tip: Add a calendar reminder every 30 days. HardyPaw even offers auto-ship options so you never forget!

What Are the Ingredients in Tri-Heart Plus for Dogs?

Tri-Heart Plus uses a dual-active formulation for maximum parasite control:

These ingredients are the same as those in Heartgard Plus, ensuring therapeutic equivalency at a better value.

Are There Side Effects or Warnings for Tri-Heart Plus?

Possible Side Effects:

• Vomiting or diarrhea (usually mild)
  
• Lethargy or drooling
  
• Loss of appetite
  
• Rare cases of allergic reactions
  

Seek veterinary care immediately if your dog shows signs of:

• Facial swelling
  
• Hives
  
• Difficulty breathing
  
• Ataxia (lack of coordination)
  

Safety Warnings:

• Not for human use
  
• Store out of reach of children and other pets
  
• Use in Collies and herding breeds with caution, as they may be more sensitive to Ivermectin
  
• Do not use in puppies under 6 weeks or in animals already infected with adult heartworms without a vet exam
  

How to Store and Handle Tri-Heart Plus Chewables?

• Store at controlled room temperature (68–77°F)
  
• Keep blister pack intact until use
  
• Do not refrigerate or expose to extreme heat
  

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

How to Order Tri-Heart Plus Online from HardyPaw

Ordering from HardyPaw is simple:

1. Upload your dog’s valid prescription or have us contact your vet.
   
2. Add the correct weight-range product to your cart (this one’s for 1–25 lbs).
   
3. Choose one-time or auto-ship for worry-free refills.
   
4. Sit back and relax—your pet’s protection is on the way.
   

Tri-Heart Plus for Dogs up to 25 lbs FAQs

What is Tri-Heart Plus for Dogs used for?

Tri-Heart Plus is used to prevent heartworm disease and control hookworms and roundworms in dogs. It's a once-monthly oral medication designed for dogs weighing 1–25 lbs.

Is Tri-Heart Plus as effective as Heartgard Plus?

Yes, Tri-Heart Plus contains the same active ingredients—Ivermectin and Pyrantel—and offers the same level of protection as Heartgard Plus but at a more affordable price.

Can puppies take Tri-Heart Plus?

Yes, Tri-Heart Plus is safe for puppies aged 6 weeks and older, provided they weigh at least 1 pound. Always consult your vet before starting treatment.

Do I need a prescription for Tri-Heart Plus?

Yes, Tri-Heart Plus is a prescription-only medication, and you'll need authorization from a licensed veterinarian to purchase it.

What happens if I miss a dose of Tri-Heart Plus?

If a dose is missed by more than 30 days, your dog may be at risk for heartworm infection. Contact your veterinarian before resuming the medication.

How long does Tri-Heart Plus take to start working?

Tri-Heart Plus begins killing heartworm larvae and intestinal parasites within hours of ingestion. The active ingredients, Ivermectin and Pyrantel, act quickly to prevent heartworm maturation and eliminate roundworms and hookworms.

Can Tri-Heart Plus be given with other medications?

Tri-Heart Plus can be safely given with most flea, tick, and routine medications. Always inform your veterinarian about all supplements or drugs your dog is taking to avoid potential interactions or contraindications.

Does Tri-Heart Plus protect against fleas or ticks?

Tri-Heart Plus does not kill or repel fleas or ticks. It is strictly a heartworm and intestinal parasite preventative. For full protection, use a separate flea and tick control product like NexGard or Frontline in combination.

Is Tri-Heart Plus safe for pregnant or nursing dogs?

Tri-Heart Plus has not been evaluated in breeding, pregnant, or lactating dogs. Always consult your veterinarian before administering this medication to ensure safety based on your dog’s condition and reproductive status.

What should I do if my dog spits out the Tri-Heart Plus chew?

If your dog spits out the chew, try hiding it in food or a treat. Ensure the entire dose is consumed. If not fully ingested, your dog may not be protected. If issues persist, consult your vet for alternative administration methods.

Clinical Research

• https://www.msdvetmanual.com/dog-owners/digestive-disorders-of-dogs/gastrointestinal-parasites-of-dogs
• https://www.petmd.com/pet-medication/pyrantel-pamoate
• https://www.fda.gov/safety/medical-product-safety-information/ivermectin-intended-animals-letter-stakeholders-do-not-use-humans-treatment-covid-19