PetPrevea Advanced Topical Treatment for Dogs over 55 lbs (4 doses)

Monthly Pest Defense with Five Benefits for Extra-Large Dogs

Product Description

Extra-large dogs are more likely to be outdoors, making them vulnerable to pests; they need robust protection. PetPrevea Advanced offers a monthly topical treatment for dogs over 55 lbs, blending imidacloprid, permethrin, and pyriproxyfen to effectively repel and eliminate fleas, ticks, mosquitoes, biting flies, and lice with just one dose. This waterproof, fragrance-free solution works quickly, destroying existing fleas within 12 hours, and keeps dogs aged seven weeks and up protected throughout every season and activity.

Benefits

• 5-Way Pest Protection: Repels and kills fleas, ticks, mosquitoes, biting flies, and lice with one convenient monthly application.
• Fast Flea Kill: Kills existing fleas within 12 hours and eliminates reinfesting fleas within 2 hours of a single application.
• Broad Tick Coverage: Repels and kills Deer Ticks, American Dog Ticks, Brown Dog Ticks, and Lone Star Ticks for up to four weeks.
• Mosquito Repellent: Repels and kills mosquitoes for up to four weeks, preventing blood feeding on treated dogs.
• Waterproof & Fragrance-Free: Remains fully effective after bathing and swimming; contains no added scents for sensitive dogs.

Ingredients

Active Ingredients

*cis/trans ratio: Max 55% (±) cis and min 45% (±) trans

Variants

Small Dogs, 5–10 lbs

Medium Dogs, 11–20 lbs

Large Dogs, 21–55 lbs

Extra-Large Dogs, Over 55 lbs

How to Use

Directions for Use

• Open the Tube: Remove the inner tray from the carton, grasp one tube firmly, push the cap down, and twist counter-clockwise to remove it; reverse the cap, place it back on, and twist to break the seal before removing.
• Ensure Dog is Dry: The dog must be completely dry before application and must remain dry for 24 hours after treatment.
• Multi-Spot Application: Apply the entire contents of the tube evenly to 3–4 spots along the dog's back, from the shoulder blades to the base of the tail.
• Apply at Skin Level: At each spot, part the hair until the skin is visible, place the tube tip directly on the skin, and squeeze gently to apply without runoff.
• Repeat Monthly: Reapply once every month; in severe infestations, retreatment once a week is permitted, not to exceed 4 weeks, then return to a monthly schedule.

Additional Information

Precautions

Hazards to Humans

• Eye Injury Hazard: Causes substantial but temporary eye injury; avoid all contact with eyes or clothing during and after application.
• Harmful if Swallowed: Harmful if swallowed; wash hands thoroughly with soap and water after every handling, before eating or drinking.
• Skin Sensitivity Risk: Prolonged or repeated skin contact may cause allergic reactions; remove and wash any contaminated clothing immediately.

Hazards to Domestic Animals

• Age & Weight Restriction: For use only on dogs and puppies 7 weeks of age and older weighing over 55 lbs; do not use on lighter dogs.
• Fatal to Cats: May be fatal to cats; never apply to cats and keep treated dogs away from cats for 24 hours after application.
• Dogs Only: For external use on dogs only; do not use on rabbits, cats, kittens, or any other animals under any circumstances.
• Keep Dog Dry: Do not bathe or allow swimming for 24 hours after application; keep the dog off furniture until the treated area is fully dry.
• Environmental Hazard: Extremely toxic to aquatic organisms, including fish and invertebrates; do not contaminate water when disposing of product or packaging.
• Consult Your Vet: Speak to a veterinarian before using on dogs that are medicated, debilitated, aged, pregnant, or nursing.

Possible Side Effects

• Skin Irritation: May cause redness, scratching, or visible discomfort at or around the application site after use.
• Gastrointestinal Signs: Vomiting or diarrhea has been reported in some dogs following topical application of this treatment.
• Lethargy or Agitation: Signs of lethargy or agitation have been reported; contact a veterinarian promptly if these occur after application.
• Sensitivity Reactions: Individual sensitivities may develop over time; if signs persist or worsen, bathe with mild soap, rinse thoroughly, and seek veterinary care.

Shipping & Returns

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: What pests does this topical treatment protect extra-large dogs against?

Ans: This once-a-month formula provides five-way protection, repelling and killing fleas, ticks, mosquitoes, biting flies, and lice with a single application. It targets all life stages of fleas and ticks, making it one of the broadest-coverage topical treatments available for extra-large dogs.

Q2: How quickly does this treatment kill fleas after application on extra-large dogs?

Ans: It kills existing fleas within 12 hours of application. Reinfesting fleas are eliminated within 2 hours, with protection against further flea infestation lasting at least four weeks. Monthly reapplication is required for continuous flea and tick control.

Q3: How is this treatment applied to extra-large dogs?

Ans: The entire tube contents are applied evenly across 3–4 spots from the shoulder blades to the base of the tail. At each spot, hair is parted to expose the skin before applying. This multi-spot method ensures full, even coverage across the entire body surface.

Q4: Why is this treatment dangerous for cats?

Ans: The formula contains permethrin, a synthetic pyrethroid that is highly toxic to cats and can be fatal if applied to them or ingested. Treated dogs must be kept away from cats for 24 hours after application, and this product must never be applied to cats under any circumstances.

Q5: Which tick species does this treatment protect extra-large dogs against?

Ans: It repels and kills Deer Ticks that may transmit Lyme disease, American Dog Ticks that may transmit Rocky Mountain spotted fever, Brown Dog Ticks that may transmit Ehrlichiosis, and Lone Star Ticks that may also transmit Ehrlichiosis for up to four weeks per dose.

Q6: Is this treatment waterproof after application?

Ans: Yes, the formula is fully waterproof and remains effective after bathing, swimming, rain, and exposure to sunlight. However, the dog must stay completely dry for 24 hours immediately after application to allow the product to properly absorb and bond to the skin.

Q7: Can this treatment also repel mosquitoes from extra-large dogs?

Ans: Yes, permethrin repels and kills mosquitoes for up to four weeks per treatment, preventing blood feeding on treated dogs. This added protection is especially valuable for large, active dogs that spend significant time outdoors in high-mosquito environments.

Q8: What should I do if an extra-large dog shows a reaction after application?

Ans: If side effects such as skin irritation, lethargy, or agitation appear, consult a veterinarian immediately. For emergencies, call 1-833-571-1532, available 24 hours a day, seven days a week. Have the product container on hand when calling for the most accurate guidance.

Q9: Can pre-existing flea pupae in the environment still hatch after treatment?

Ans: Yes, pre-existing flea pupae may continue to emerge for six weeks or longer, depending on climatic conditions. Year-round monthly treatment is the most effective strategy to prevent reinfestation from environmental flea stages, especially for large dogs with outdoor access.