PetPrevea Advanced Topical Treatment for Dogs 21-55 lbs (4 doses)

5-Way Monthly Pest Protection for Large Dogs

Product Description

Most flea and tick treatments stop at two threats. PetPrevea Advanced targets five. Designed for large dogs weighing 21–55 lbs, this once-a-month topical formula combines imidacloprid, permethrin, and pyriproxyfen to repel and kill fleas, ticks, mosquitoes, biting flies, and lice in a single monthly application. Waterproof, fragrance-free, and fast-acting, it kills existing fleas within 12 hours and keeps dogs 7 weeks and older protected through any activity, weather, or season.

Benefits

• 5-Way Pest Protection: Repels and kills fleas, ticks, mosquitoes, biting flies, and lice with one monthly topical application.
• Fast-Acting Formula: Kills existing fleas within 12 hours and eliminates reinfesting fleas within just 2 hours of application.
• Tick & Lyme Defense: Repels and kills Deer Ticks, American Dog Ticks, Brown Dog Ticks, and Lone Star Ticks for up to four weeks.
• Mosquito Repellent: Repels and kills mosquitoes for up to four weeks, preventing blood feeding on treated dogs.
• Waterproof & Long-Lasting: Remains fully effective after bathing, swimming, rain, and sunlight exposure throughout the month.

Ingredients

Active Ingredients

*cis/trans ratio: Max 55% (±) cis and min 45% (±) trans

Variants

Small Dogs, 5–10 lbs

Medium Dogs, 11–20 lbs

Large Dogs, 21–55 lbs

Extra-Large Dogs, over 55 lbs

How to Use

Directions for Use

• Open the Tube: Remove the inner tray from the carton, grasp one tube firmly, push the cap down, and twist counter-clockwise to remove it; reverse the cap, place it back on, and twist to break the seal before removing.
• Ensure Dog is Dry: The dog must be completely dry before application and must remain dry for 24 hours after treatment.
• Multi-Spot Application: Apply the entire contents evenly to 3–4 spots along the dog's back, from the shoulder blades to the base of the tail.
• Apply at Skin Level: At each spot, part the hair until the skin is visible, place the tube tip directly on the skin, and squeeze gently to apply.
• Repeat Monthly: Reapply once every month for continuous protection; in severe infestations, retreatment once a week is permitted, not to exceed 4 weeks.

Additional Information

Precautions

• Eye Injury Hazard: Causes substantial but temporary eye injury in humans; avoid all contact with eyes or clothing during and after application.
• Harmful if Swallowed: Product is harmful if swallowed; wash hands thoroughly with soap and water after every handling before eating or drinking.
• Skin Sensitivity Risk: Prolonged or frequently repeated skin contact may cause allergic reactions; remove and wash any contaminated clothing immediately.
• Fatal to Cats: Do not use on cats. This product may be fatal to cats; keep treated dogs away from cats for 24 hours after application.
• Age & Weight Restriction: For use only on dogs and puppies 7 weeks of age and older weighing between 21 and 55 lbs.
• Dogs Only: For external use on dogs only; do not use on rabbits, cats, kittens, or any other animals under any circumstances.
• Keep Dog Dry: Do not bathe the dog or allow swimming for 24 hours after application; keep the dog off furniture until the treated area is fully dry.
• Environmental Hazard: Extremely toxic to aquatic organisms, including fish and invertebrates; do not contaminate water when disposing of product or packaging.
• Consult Your Vet: Speak to a veterinarian before use on dogs that are medicated, debilitated, aged, pregnant, or nursing.

Possible Side Effects

• Skin Irritation: May cause redness, scratching, or visible discomfort at or around the application site after use.
• Gastrointestinal Signs: Vomiting or diarrhea has been reported in some dogs following topical application of this treatment.
• Lethargy or Agitation: Signs of lethargy or agitation have been reported in some dogs; contact a veterinarian promptly if these occur.
• Sensitivity Reactions: Individual sensitivities may develop over time; if signs persist or worsen, bathe with mild soap, rinse thoroughly, and seek veterinary care.

Shipping & Returns

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: How many pests does this topical treatment protect against?

Ans: This formula provides five-way protection, repelling and killing fleas, ticks, mosquitoes, biting flies, and lice in one monthly application. It targets all life stages of fleas and ticks, making it one of the broadest-coverage topical treatments available for large dogs.

Q2: How quickly does this treatment kill fleas after application?

Ans: The formula kills existing fleas on dogs within 12 hours of application. Reinfesting fleas are killed within 2 hours, and protection against further infestation lasts at least 4 weeks. Monthly reapplication is required for continuous flea and tick control.

Q3: Which tick species does this treatment protect against?

Ans: It repels and kills Deer Ticks that may transmit Lyme disease, American Dog Ticks that may transmit Rocky Mountain spotted fever, Brown Dog Ticks that may transmit Ehrlichiosis, and Lone Star Ticks that may also transmit Ehrlichiosis for up to four weeks per application.

Q4: Why is this treatment dangerous for cats?

Ans: The formula contains permethrin, a synthetic pyrethroid that is highly toxic to cats and can be fatal if applied to them or ingested. Treated dogs must be kept away from cats for 24 hours after application, and the product must never be applied to cats under any circumstances.

Q5: Does this treatment repel mosquitoes as well as fleas and ticks?

Ans: Yes, permethrin in this formula repels and kills mosquitoes for up to four weeks per treatment, preventing mosquitoes from blood-feeding on treated dogs. This added coverage makes it especially valuable for dogs that spend significant time in outdoor or wooded environments.

Q6: Is this treatment waterproof after application?

Ans: Yes, the formula is fully waterproof and remains effective after bathing, swimming, rain, and exposure to sunlight. However, the dog must stay completely dry for 24 hours immediately after application to allow the product to properly absorb into the skin.

Q7: Can this treatment be used on puppies?

Ans: It is approved for use in dogs and puppies at least 7 weeks old and weighing at least 21 lbs. Do not apply to younger puppies or those below the minimum weight, as doing so may cause adverse reactions or serious harm.

Q8: What should I do if my dog shows a reaction after application?

Ans: If side effects such as skin irritation, lethargy, or agitation appear, consult a veterinarian immediately. For emergencies, call 1-833-571-1532, available 24 hours a day, seven days a week. Have the product container on hand when calling for the most accurate guidance.

Q9: Can pre-existing flea pupae in the environment still hatch after treatment?

Ans: Yes, pre-existing flea pupae in the environment may continue to emerge for six weeks or longer, depending on climatic conditions. Year-round monthly treatment is the most effective way to prevent reinfestation from environmental flea stages and outdoor exposure.

Q10: Can this product be used alongside other pest control treatments?

Ans: Do not combine with other pesticide products containing permethrin, imidacloprid, or pyriproxyfen. Overdosing can cause serious illness. Consult a veterinarian before using this treatment alongside any other flea, tick, or pest control product on the same dog.